祁捷斐,李乃祥,潘小虎,王宇,乌婧,王华平
QI Jie-fei,LI Nai-xiang,PAN Xiao-hu,WANG Yu,WU Jing,WANG Hua-ping

• 1:东华大学材料科学与工程学院
• 2:纤维材料改性国家重点实验室
• 3:中国石化仪征化纤有限责任公司
• 4:东华大学纺织产业关键技术协同创新中心

摘要(Abstract)：

聚丁二酸丁二醇酯(PBS)是一种具有广阔发展前景的生物基聚酯品种,但由于其分子链段柔性较高并且结晶度高,在实际应用过程中仍然面临热性能、力学性能、降解性能不足的弊端。选用条件更为温和的酶催化体系,以丁二酸二乙酯、己二酸二乙酯、丁二醇为原料,Novozym-435(固定化CALB酶)为催化剂,甲苯为溶剂,合成制备了一系列高分子质量的聚(丁二酸丁二醇-co-己二酸丁二醇)(PBSA)三元共聚酯。在反应温度80℃、酶的质量分数为10%的条件下,所制备的PBS与PBSA共聚酯的数均分子质量在18 400～21 200 g/mol,多分散性指数在1.7～2.0之间。采用核磁共振谱仪对制备的共聚酯产物的化学结构进行了表征。TGA结果表明,酶催化体系下的PBSA共聚酯的热稳定性要高于熔融体系下的产物。DSC与WAXD的结果表明,引入己二酸链段后,PBS的结晶能力下降。酶催化反应避免了重金属催化剂的使用,进一步拓宽了PBS在生物医药领域范围的潜在应用。
As an essential biodegradable polyester,poly(butylene succinate) is a highly promising species.However,due to the high flexibility of its segments and high crystallinity,poly(butylene succinate) is still restricted for wider applications because of its low thermal and mechanical properties and unsatisfactory biodegradability.A series of high molecular weight poly(butylene succinate-co-butylene adipate)(PBSA) copolyesters constructed with diethyl succinate,diethyl adipate,1,4-butanediol are synthesized by using a moderate enzyme catalyst Novozym-435(immobilized Candida antarctica lipase B) through the azerotrope method.Under the reaction temperature 80℃ and the enzyme concentration 10%,the Mn value of prepared PBS and PBSA is in the range of 18 400～21 200 g/mol,and its corresponding molecular weight distribution is in the range of 1.7～2.0.TGA results show that the thermal stability of the samples from enzyme catalyzed polymerization is higher than that of the products from the melten polymerization.DSC and WAXD results show that the crystallization ability of PBS reduced after adipate acid is introduced.Additionally,since the use of metal catalysts is avoided in the reaction,the potential application of PBS in the biomedical field is further widened.

关键词(KeyWords)： 聚丁二酸丁二醇酯;酶催化;CALB;高分子质量
poly(butylene succinate);lipase catalyze;CALB;high molecular weight

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(51803026);; 中央高校基本科研业务费专项资金资助项目(2232018D3-35);; 中国石油化工有限公司研发项目(420039-1)

作者(Author): 祁捷斐,李乃祥,潘小虎,王宇,乌婧,王华平
QI Jie-fei,LI Nai-xiang,PAN Xiao-hu,WANG Yu,WU Jing,WANG Hua-ping

DOI: 10.16090/j.cnki.hcxw.2020.08.002

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