合成纤维

2017, v.46;No.335(01) 34-36

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不同共聚比例的PLGA静电纺丝膜的结构与性能
Study on Structure and Properties of PLGA Nanofibrous Membrane with Different Copolymerization Ratio

陈桂香;黄飞燕;
CHEN Gui-xiang;HUANG Fei-yan;Jiangsu Engineering Vocational College;

摘要(Abstract):

研究了丙交酯(LA)与乙交酯(GA)不同共聚比例的聚乳酸-乙醇酸(PLGA)纤维膜的表面形态、力学性能及体外降解性能,结果表明:PLGA具有较宽的降解可调性;随着GA比例的增加,纤维直径变小,断裂强度减小,断裂伸长率增大,降解速率增大;可以通过调节LA、GA比例调控支架材料的梯度降解性能,满足临床需求。
The surface morphology, mechanical properties and degradation performance of PLGA fiber mem-brane with different copolymer monomer ratio were studied. The results showed that the degradation ofPLGA had widely adjustable. With the increase of proportion of GA, the fiber diameter and the breakingstrength decreased, and the elongation at break and the degradation rate increased. As a result, in orde tomeet clinical needs, different LA/GA copolymerization proportion could be adjusted to contral the gradientof scaffold degradation

关键词(KeyWords): PLGA;共聚比例;形貌结构;降解性能
PLGA;copolymerization ratio;morphology structure;degradation performance

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基金项目(Foundation): 2013年度南通纺织职业技术学院自然科学研究项目(FK-KY/2013/14)

作者(Author): 陈桂香;黄飞燕;
CHEN Gui-xiang;HUANG Fei-yan;Jiangsu Engineering Vocational College;

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