丝素/聚乳酸静电纺丝的研究Investigation on Electrospinning of SF/PLA Fiber
缪秋菊,左保齐,秦志忠,韩林,夏永林
MIAO Qiu-ju1, ZUO Bao-qi2, QIN Zhi-zhong2, HAN lin2, XIA Yong-lin2 (1. Suzhou Institute of Trade & Commerce
摘要(Abstract):
以具有一定生物活性、细胞黏附性能好的丝素蛋白与降解性能优良的聚乳酸复合,以静电纺丝方法形成20%丝素与80%聚乳酸的丝素/聚乳酸共混纤维非织造网。通过扫描电子显微镜研究其形态,X-射线衍射、红外光谱等分析研究其聚集态结构变化。研究表明:丝素/聚乳酸静电纺的纤维直径与电压、接收距离大小和后处理方法有关;不同后处理方法对丝素/聚乳酸静电纺纤维的结晶结构有较大影响。
The SF/PLA blend fiber made of 20 % SF (silk fibroin ) and 80 % PLA was prepared by electrospinning. The morphology and structural transformation of the fiber were investigated by scanning electron microscope, X-ray scattering and infrared spectrum respectively. The results showed the diameter of SF/PLA fiber was related to voltage, receiver distance and post-treatment. The different post-treatment had more influence on crystalline structure of SF/PLA fiber.
关键词(KeyWords):
静电纺丝;丝素;聚乳酸;共混;结构
electrospinning, silk fibroin, PLA, blend, structure
基金项目(Foundation): 国家973课题(2005CB623906)资助。
作者(Author):
缪秋菊,左保齐,秦志忠,韩林,夏永林
MIAO Qiu-ju1, ZUO Bao-qi2, QIN Zhi-zhong2, HAN lin2, XIA Yong-lin2 (1. Suzhou Institute of Trade & Commerce
参考文献(References):
- [1]宁丽,薛淼等.皮肤再生膜的生物相容性系列研究[J].中国修复重建外科杂志,2000,14(1):44-48.
- [2]Altman G H,Diaz F,Kaplan D L et al.Silk-based biomaterials[J].Biomaterials,2003,24(3):401-416.
- [3]Skutsu F,Inoki M,Uei H,et al.Synthesis of poly(1actic acid)by di-rect polycondensation of lactic acid using l,l'carbonyldiimidazole,N,N,N',N-tetramelhylchloroform amidinium chloride,and N,N'-dicyclo-hexylcarbodiimide as condensing agent[J].Polymer,1998,30(5):421.
- [4]Moon S I,Lee C W et al.Melt/solid polycondensation of L-lactic acid:analternative route to poly(L lactic acid)with high molecular weight[J].Polymer,2001,42(11):5059.
- [5]Moon S I,Lee C W et al.Melt polyconden sation of L-lactic acid with Sn(Ⅱ)catalysts activate by variOUS proton acids:A direct manufacturing route to high weight poly(L-lactic acid)[J].J Polym Sci Part A:Polym Chem,2000,38(9):1673.
- [6]Jacobsena S,Fritza H G.Single-step reactive extrusion of PLLA in a corotating twin-screw extruder promoted by2ethylhexanoic acid tin(Ⅱ)salt and triphenylphosphine[J].Polymer,2000,41(9):3395.
- [7]姚军燕,秦能,杨青芳.生物医用高分子材料聚乳酸的成型方法研究[J].塑料工业,2004,32(10):6-8.
- [8]Jun Wuk Park,Seung Soon Im.Phase behavior and morphology in blends of poly(L-lactic acid)and poly(butylene succinate)[J].Journal of Applied Polymer Science,2002,86(3):647-655.
- [9]钱国坻,姚予梁.红外光谱在蚕丝纤维结构研究中的应用[J].苏州丝绸工学院学报,1983,4:26-30.
- [10]范宁伟,翦英红,景丽洁.聚乳酸的合成及分析[J].合成化学,2003,6:531.