再生丝素蛋白/聚乙烯醇共混纳米纤维的静电纺丝研究Study on SF/PVA Blending Nanofibers by Electrospinning
刘芸,薛华育,戴礼兴
LIU Yun, XUE Hua-yu, DAI Li-xing(College of Polymer Science and Engineering
摘要(Abstract)：
以静电纺丝方法制备再生丝素蛋白/聚乙烯醇共混纳米纤维。研究了共混配比、溶液浓度、添加剂含量及电纺电压、喷丝距离等因素对纤维成形及纤维有关性能的影响。研究表明:与聚乙烯醇共混后再生丝素纤维的柔韧性有一定改善,适当增加PVA在共混物中的含量、提高纺丝液浓度以及纺丝电压有利于改善共混溶液的可纺性。另外,加入丙三醇虽可使纤维直径的均匀性有所提高,但却不利于纤维成形。
In this paper, silk fibroin and polyvinyl alcohol (SF/PVA) blend nanofibers were made by electrospinning and its dominating factors, such as blending ratio, concentration of spinning solution, additive, voltage, and distance between the capillary and collecting screen were studied. By blending with PVA, the rigidity and fragile properties of regenerated SF could be improved to some extent. With increasing the amount of PVA in the blend, concentration of spinning solution and the voltage of electrospinning, spinnability of the solution could be favored. Besides, the uniformity of the nanofibers could be increased by the addition of glycerin, but the coagulation effect of the nanofibers was decreased.
关键词(KeyWords)：
静电纺丝;丝素;聚乙烯醇;共混;纳米纤维
electrospinning, SF, PVA, blend, nanofiber
基金项目(Foundation): 国家973计划资助(编号2005CB623906);; 江苏省高校自然基金项目(编号04KJB430132)。
作者(Author):
刘芸,薛华育,戴礼兴
LIU Yun, XUE Hua-yu, DAI Li-xing(College of Polymer Science and Engineering
参考文献(References)：
- [1]Kaplan D,Adams WW,et al.Silk polymers:materials science and biotechnology,Washington,DC:ACS,1994.
- [2]Sakabe H,Ito H,et al.In vivo blood compatibility of regenerated silk fibroin.Sen-i Gakkaishi,1989,45:487-90.
- [3]Park WH,Ha WS,et al.Relationships between antithrombogenicity and surface free energy of regenerated silk fibroin films.Fibers Polym,2001,2:58-63.
- [4]Santin M,Motta A,et al.In vitro evaluation of the inflammatory potential of the silk fibroin.J Biomed Mater Res,1999,46:382-389.
- [5]孙东豪等.聚乙烯醇/丝素蛋白共混膜的结构与性能研究.丝绸,2001,11:6-8.
- [6]尹桂波,张幼珠.静电纺再生丝素纳米纤维形态结构的研究.丝绸,2005,2:16-18.
- [7]Byung-Moo Min,Byung-Moo Min.Electrospinning of silk fibroin nanofibers and its effect on the adhesion and spreading of normal human keratinocytes and fibroblasts in vitro.Biomaterials,2004,(25):1289-1297.
- [8]徐明,戴宏钦等.水溶性纳米级纤维毡的纺制工艺.苏州大学学报(工科版),2005,25(1):14-18.
- [9]戴礼兴等.多元醇对SF/PVA共混体系的增容作用.纺织学报,2000,21(6):18-20.